Beyond The Reference Genome: How pangenomics is changing the game
/Reference genomes have long been the backbone of genomic research. These 'one-size-fits-all' representations are typically constructed from sequencing projects that use just a single representative. While there is no doubt that they have been invaluable, they fall short in capturing the full genetic diversity within a species - who’s to say that the one individual chosen to be sequenced has the full gamut of every piece of information in their genome?
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