New Services at AGRF

 

Polygenic Risk Scores: Bringing Genetic Risk to Light

 

FEB 2025

Powered by Illumina and Allelica, our Polygenic Risk Score (PRS) analysis service provides researchers with a cost-effective and standardised approach to genetic risk assessment, seamlessly integrating genome-wide SNP or WGS data into actionable insights. 

Polygenic Risk Scores aggregate the effects of thousands of genetic variants across the genome to assess an individual’s predisposition to over 20 common diseases including cardiovascular disease, various cancers and diabetes.  This enables a more comprehensive genetic risk assessment, aiding early detection, prevention, and personalised medicine.  

  • Standardised, validated PRS models based on large-scale GWAS studies 

  • Automated, accurate PRS computation with Allelica’s PREDICT pipeline 

  • Customisable PRS options for different traits and diseases 

  • Disease risk prediction with over 20 common diseases including cardiovascular disease, cancer, diabetes and more 

  • Stratified screening programs for high-risk individuals

  • Population Research studies  

Olink® Proteomics Target 96 and Target 48 workflows

JAN 2025

Our local laboratory provides Australian researchers with direct access to the advanced Olink® proteomics services and has recently added Target 96 and Target 48 workflows.

Olink Target enables reliable protein quantitation across multiple applications, with pre-designed panels for oncology, immunology, cardiology, and neurology.

Whether exploring disease mechanisms, identifying therapeutic targets, or developing diagnostics, Olink Target delivers actionable insights quickly. With high data quality, low sample requirements, and scalability, it’s ideal for advancing research in complex biological systems and personalised medicine.

 

Whole Plasmid and Amplicon Express Service

JULY 2024

AGRF’s Whole Plasmid and Amplicon Express service is a small-scale next generation sequencing (NGS) service designed to make the Illumina short read platform accessible to researchers for small projects, or genomes.

Key advantages:

  • Whole plasmid sequencing

  • Transposase library preparation

  • Guaranteed data (5,000 reads/sample)

  • Plasmid de novo assembly included

  • Suitable for small amplicon sequencing (150-250bp)