A genomic approach to transform liver and renal transplants

A genomic approach to transform liver and renal transplants

Leading efforts to improve transplant outcomes is Professor Paul James, a Clinical Geneticist and Director of the Parkville Familial Cancer Centre at Peter MacCallum Cancer Centre and Royal Melbourne Hospital. He leads a Melbourne Genomic Health Alliance funded Clinical Change Project, which seeks to “get more out of the genome” and use genetic insights to personalise patient care in high-intensity settings, such as organ transplants.

AGRF plays a crucial role in this initiative by providing genomic sequencing and analysis to patients with upcoming transplant procedures. The workflow utilises a multi-platform approach, combining low pass Whole Genome Sequencing, Illumina Global Screening Array and Sanger Sequencing to generate high-quality data to inform comprehensive genomic reports for clinicians and pharmacists.

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Five Women in Science - Associate Professor Tu Nguyen-Dumont

Five Women in Science - Associate Professor Tu Nguyen-Dumont

Associate Professor Tu Nguyen-Dumont from Monash University. Associate Professor Tu Nguyen-Dumont serves as the genomics and bioinformatics lead in several multidisciplinary teams dedicated to exploring and defining genomic variations associated with cancer risk, cancer development, recurrence, and response to treatment.

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How Genomics Is Making Phage Therapy a Reality

How Genomics Is Making Phage Therapy a Reality

Bacteria have long been a challenging adversary in the world of medicine. Antibiotics have been a primary treatment for bacterial infections, but their overuse has led to the emergence of antibiotic-resistant (AMR) bacteria, causing a significant health threat (refer health economics report commissioned by Iredell, Lin et al, Phage Australia). A promising revival of phage therapy is set to combat AMR infections more effectively and with fewer side effects than antibiotics.

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ZERO: A hopeful future for children with cancer

ZERO: A hopeful future for children with cancer

In Australia, more than 1,000 children and adolescents are diagnosed with cancer every year. While the overall survival rate for childhood cancer is now over 80%, for some types of cancer the rate is much lower. Every week, three young lives are lost to cancer – more than to any other disease.

In 2021, AGRF joined a unique collaboration aiming to improve these statistics, becoming a key partner in the Zero Childhood Cancer Program (ZERO), Australia’s first national precision medicine program for children with cancer..

Learn how AGRF are helping to make a difference.

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