Your Partners in Epigenetics

Whole Genome Methylation Sequencing

Use Next Generation Sequencing to detect DNA methylation across the entire genome, including CpG and less common CHG and CHH contexts.

Use whole genome or genome-wide methylation sequencing to identify differentially methylated regions, and for discovery of epigenetic biomarkers.

 

Genome Wide Methylation Analysis

Use EPIC methylation arrays to screen a human’s whole genome methylation pattern to identify variable genomic regions that may be contributing to gene expression variation or the phenotypic outcome.

Suitable for all mammalian genomes, Reduced Representation Bisulfite Sequencing detects genome-wide CpG methylation patterns for identification of differentially methylated regions (DMRs).

 

Targeted Methylation Sequencing

Rapid, automated measurement of methylation at multiple CpG sites, including:

  • Orthologous validation of DMRs identified by NGS or Arrays in larger cohorts

  • Accurate measurement of methylation at specific CpG sites

  • Measurement of methylation at CpG sites in difficult sequence regions or dense CpG islands

We also offer custom amplicon methylation. Please contact your account manager using the link below for more information.

 

Our Epigenetics Services

Analysis of DNA methylation, DNA demethylation, and the functional effects in these changes are of increasing interest to epigenetics researchers in developmental programming, cell differentiation, disease identification, and therapeutic development.

From whole genome studies to quantitative customised analyses we can help you analyse methylation patterns using a variety technologies.

Our Epigenetics services include:

  • Whole genome methylation screening

  • Gene and promoter methylation discovery

  • Reduced Representation Bisulfite Sequencing

  • MethylSeq Next Generation Sequencing

  • Targeted sites and methylation validations

  • Discovery via Sanger sequencing

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Advance your genomic research.

Your Partners in Epigenetics.