Investigate pharmacogenetic biomarkers associated with drug metabolism

 

What is pharmacogenomics?

Pharmacogenomics is the study of how genetic makeup determines the response to a therapeutic intervention by combining traditional pharmaceutical sciences such as biochemistry with an understanding of DNA variations in the human genome.

 

AGRF's SNP Genotyping services

For projects that investigate pharmacogenetic variations, the Agena Bioscience MassARRAY System enables cost-effective detection of germline variations that cause differences in drug distribution, efficacy, metabolism, and toxicity.

This application can be used for routine pharmacogenetic testing to determine drug metabolizer status with a pre-designed iPLEX ADME PGx panel from Agena Bioscience. Alternatively, validate your own PGx markers by creating your own panel comprising SNPs, insertions and deletions, with the custom designed pathway to screen hundreds of samples economically.

The Sequenom Custom Genotyping service is NATA 17025 accredited and a certified service provider for Mass Array genotyping so you can be assured of reliable data quality.

 

Our genotyping platforms enable applications from genome-wide linkage and association studies to customised fine mapping. With a suite of genotyping solutions we can customise your genotyping project to the most suitable assay technology on one of our platforms.

     

 

Our customised approach

We know every project is unique. That is why we have a flexible approach to accommodate your research goal, with a broad range of applications offering flexible solutions.

You can expect proven assays and accuracy to ensure that projects are completed in accordance with our quality standards.

We offer support throughout the lifetime of your project whether it be, experimental design advice or to answer any questions regarding sample status or analysis options.

Get in touch with your account manager to learn more.